Review: Drinkin’ Mate Hangover Defense

Review: Drinkin’ Mate Hangover Defense


There’s good news and bad news about Drinkin’ Mate, another entry into the growing category of hangover prevention remedies.

First the good: Compared to the field, Drinkin’ Mate is the best-tasting hangover preventer around. It’s an effervescent pill (like an Alka-Seltzer). Just drop it in a few ounces of water, and you get a fizzy, fruity drink that goes down pretty quickly and painlessly. Made primarily from guava leaf extract, it’s a bit tropical and a lot berry-like (the only version seems to be “wild berry flavor”), very sweet (thanks to shots of sorbitol and sucralose). Unlike some of those nasty, syrupy hangover cures, you won’t have to choke this one down before you go out. (The company also says you can take it after drinking to avoid a hangover.)

Now the bad news: For me, Drinkin’ Mate did absolutely nothing to prevent a hangover. The one I’ve been nursing today is the outright worst in recent memory, which makes me wonder how effective guava leaf could possibly be at fighting off the headache from a half-dozen glasses of whiskey and wine. The only other real active ingredient here is sodium bicarbonate, pretty tame stuff that would have no hope against a major alco-binge, at least it didn’t for me.

As always, these remedies are often a shot in the dark, and some work for some drinkers and not at all for others. Your mileage may vary, but while I didn’t get any benefit from Drinkin’ Mate, at least the act of drinking Drinkin’ Mate didn’t make me want to throw up on the spot.

C / $24 for 12 tablets

Drinkin' Mate Hangover Defense




Christopher Null is the founder and editor in chief of Drinkhacker. A veteran writer and journalist, he also operates Null Media, a bespoke content creation company.


  1. Rondy on July 25, 2009 at 5:27 pm

    I tried this product and it did absolutely nothing for me. Luckily I ordered the free sample, which took two whole months to get to me, and didnt have to spend any money.

  2. George on August 25, 2009 at 5:49 pm

    I tried the free sample also and it seemed to work real well for me. I also read the Vegas Weekly article where they put a bunch of products to the test and this one was ranked #1. I have been buying it at Wal-Mart and a bar by my h

  3. Bob on September 21, 2009 at 7:47 pm

    I just drank it and it was foul but not as bad as that coffee made from beans that some mountain cat ate and then shit out. Lets hope it works. I’m getting another drink and then going to bed.

  4. Mike on September 29, 2009 at 12:33 pm

    Wow, I must say I have had great experiences with Drinkinmate. Typically, I take one before I start drinking and I take a second one when I am done drinking. Also I do make sure that I have a big glass of water before I crawl into bed. I have been using the product over a year now, and have had great success. But you can drink through the product… No matter what you take at some point your body can only handle so much booze. I have reached this stage before, but even then, my hangover was way less severe than if I took nothing at all.

  5. Sheryl on March 4, 2010 at 9:57 pm

    I tried Drinkin’ Mate for the first time last night – I used one tablet before bed, after about 4 hours of drinking. I felt it was pretty effective for me. I always take two ibuprofen before gong to bed, on a night of driking, to avoid the headache. So, the headache is not my hangover complaint; what I have always struggled with is the sluggish feeling, upset stomach, and serious cravings for fat/greasy food the next day. I took the Drinkin’ Mate and did not experience any of my typical hangover symptoms. Aside from just being tired from the lack of sleep, I feel I functioned extremely well, far better than the norm. I will definitely be using this product everytime!

  6. James on March 16, 2010 at 1:46 pm

    I just got a Huge throbbing boner when I drank this.

  7. Rich on March 20, 2010 at 10:17 pm

    The most effective prevention of hangovers is Bifidus. This is a culture like Acidophilus and other bacterial strains that promote good intestinal flora. Bifidus has many strains. Go to a health food store or order on line and get the one with the most Bifidus and it’s associated strains. It must be keep under refrigeration so it’s difficult to carry while out carousing. At home or at a party where refrigeration is available, take a couple of capsules every 3-4 hours or whatever you feel is necessary to keep up with your intake. Bifidus prevents or inhibits the formation of acytaldehyde (not sure of the spelling), the stuff that causes hangovers. Try it you will be impressed.

  8. Roxanne on June 30, 2010 at 10:48 am

    Drinkin’ mate has worked great for me. And the best part was that my mom found it at the dollar store. I just drank one right when I started drinking and if I had been drinking pretty heavily I had one more before bed. I suppose everything can’t work for everyone. I would definitely recommend it though.

  9. John on August 29, 2010 at 1:57 pm

    Drinkin Mate as worked for me on numerous occasions! Not only does it help with feeling better next morning but it’s anti oxidant properties are an added bonus. This product Works!!!!!!!!

  10. Darlene Titterness on October 12, 2010 at 1:44 pm

    I get bad bad hangovers as well. I am a big fan of acidophilus. Thanks for providing good info!

  11. Lorie on November 5, 2016 at 4:16 pm

    I love this stuff . Want to buy more but I can’t find it and the link at the top is gone

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